Tetsuo Asaki

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia

Shinya Kimura, Haruna Naito, Hidekazu Segawa et al. · Blood · 2005 · 243 citations · Full text

2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug

Keiichi Kuwano, Asami Hashino, Tetsuo Asaki et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 160 citations

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension

Tetsuo Asaki, Keiichi Kuwano, Keith Morrison et al. · Journal of Medicinal Chemistry · 2015 · 86 citations

Hypertension, Cardiovascular Pharmacology, Pharmacotherapy +21

Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors

Tetsuo Asaki, Yukiteru Sugiyama, Taisuke Hamamoto et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 56 citations

Combinatorial Chemistry, Medicinal Chemistry, Derivative (Chemistry) +9

Structure–activity studies on diphenylpyrazine derivatives: A novel class of prostacyclin receptor agonists

Tetsuo Asaki, Taisuke Hamamoto, Yukiteru Sugiyama et al. · Bioorganic & Medicinal Chemistry · 2007 · 50 citations

Prostacyclin Receptor Agonists, Molecular Pharmacology, Diphenylpyrazine Derivatives +10