Shinya Kimura

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin

Shinya Kimura, Andrew W. Roberts, Donald Metcalf et al. · Proceedings of the National Academy of Sciences · 1998 · 383 citations

Bim and Bad mediate imatinib-induced killing of Bcr/Abl ⁺ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

Junya Kuroda, Hamsa Puthalakath, Mark S. Cragg et al. · Proceedings of the National Academy of Sciences · 2006 · 332 citations · Full text

Hematological Malignancy, Cell Killing, Apoptosis +11

Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial

Jun Imagawa, Hideo Tanaka, Masaya Okada et al. · The Lancet Haematology · 2015 · 297 citations

Hematological Malignancy, Medicine, Chronic Myeloid Leukaemia +11

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia

Shinya Kimura, Haruna Naito, Hidekazu Segawa et al. · Blood · 2005 · 243 citations · Full text

CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells

Linhua Jin, Yoko Tabe, Sergej Konoplev et al. · Molecular Cancer Therapeutics · 2008 · 204 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Cxcr4 Levels +17