Concepedia

A Long-Acting and Highly Selective Prostacyclin Receptor Agonist Prodrug, 2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), Ameliorates Rat Pulmonary Hypertension with Unique Relaxant Responses of Its Active Form, {4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic Acid (MRE-269), on Rat Pulmonary Artery

Keiichi Kuwano, Asami Hashino, Kumiko Noda, Keiji Kosugi, Kenji Kuwabara

Journal of Pharmacology and Experimental Therapeutics · 2008 · 89 citations · 31 references

DOI

Concepts

References

31

Bosentan Therapy for Pulmonary Arterial Hypertension

Lewis J. Rubin, David B. Badesch, Robyn J. Barst et al. · New England Journal of Medicine · 2002 · 2.7K citations · Full text

, , +17

A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension

Robyn J. Barst, Lewis J. Rubin, Walker Long et al. · New England Journal of Medicine · 1996 · 2.7K citations · Full text

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Primary Pulmonary Hypertension

Stuart Rich · Annals of Internal Medicine · 1987 · 2.1K citations

, , +12

Inhaled Iloprost for Severe Pulmonary Hypertension

Horst Olschewski, Gérald Simonneau, Nazzareno Galiè et al. · New England Journal of Medicine · 2002 · 1.8K citations · Full text

, , +12

Continuous Subcutaneous Infusion of Treprostinil, a Prostacyclin Analogue, in Patients with Pulmonary Arterial Hypertension: A Double-blind, Randomized, Placebo-controlled Trial

Gérald Simonneau, Robyn J. Barst, Nazzareno Galiè et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 1.4K citations

, , +11