Concepedia

Receptor Tissue Selectivity

Receptor Tissue Selectivity is a pharmacological property that characterizes the preferential activation or binding of a ligand to specific receptor subtypes expressed in particular tissue types, thereby eliciting tissue-specific physiological responses despite systemic distribution.

189

Publications

11.2K

Citations

999

Authors

225

Institutions

Publications per year

2017–2026

5

Variants

Tissue-selective Receptor Binding

Parents

Publications

189

Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

Sachie Suga, Kazuwa Nakao, Kiminori Hosoda et al. · Endocrinology · 1992 · 718 citations

, , +15

Tissue distribution of the P2X7 receptor

Ginetta Collo, S. Neidhart, Eric Kawashima et al. · Neuropharmacology · 1997 · 498 citations

, , +13

Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites.

V. Erspamer, Pietro Melchiorri, Giuliana Falconieri–Erspamer et al. · Proceedings of the National Academy of Sciences · 1989 · 458 citations · Full text

, , +17

Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

M J Forrest, S.-Y. Sun, Richard Hajdu et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 334 citations

, , +17

OPC-41061, a Highly Potent Human Vasopressin V2-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats

Yoshitaka Yamamura, Shigeki Nakamura, S. Itoh et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 332 citations · Full text

, , +12

1–5 of 189

Authors

999

  1. AP
    Anthony P. Davenport

    University of Cambridge, United Kingdom

    6 publications · 247 citations

    6

    h-index

  2. PD
    Pascal De Tullio

    University of Liège, Belgium

    4 publications · 139 citations

    4

    h-index

  3. PL
    Philippe Lebrun

    Université Libre de Bruxelles, Belgium

    4 publications · 139 citations

    4

    h-index

  4. BP
    Bernard Pirotte

    University of Liège, Belgium

    4 publications · 139 citations

    4

    h-index

  5. TK
    Terry Kenakin

    Research Triangle Park Foundation, United States

    4 publications · 203 citations

    4

    h-index

1–5 of 999

Institutions

225

  1. Addenbrooke's Hospital

    Cambridge, United Kingdom

    6 h-index

    10 publications

    373 citations

  2. Eli Lilly (United States)

    Indianapolis, United States

    5 h-index

    48 publications

    6.3K citations

  3. Leiden University

    Leiden, The Netherlands

    4 h-index

    25 publications

    971 citations

  4. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    8 publications

    285 citations

  5. University of Liège

    Liège, Belgium

    4 h-index

    30 publications

    1.2K citations

  6. The University of Melbourne

    Melbourne, Australia

    4 h-index

    17 publications

    419 citations

  7. Université Libre de Bruxelles

    Brussels, Belgium

    4 h-index

    27 publications

    1.2K citations

  8. Kyoto University

    Kyoto, Japan

    4 h-index

    22 publications

    8.2K citations

1–8 of 225

Venues

  1. PubMed

    Repository · 22 publications · 890 citations

    18

    h-index

  2. Journal of Medicinal Chemistry

    19 publications · 755 citations

    16

    h-index

  3. 16

    h-index

  4. British Journal of Pharmacology

    BJP · 18 publications · 781 citations

    15

    h-index

  5. Journal of Cardiovascular Pharmacology

    10 publications · 368 citations

    10

    h-index

1–5