Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: Correlation with lung surfactant protection - Concepedia

Concepedia

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Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: Correlation with lung surfactant protection

60

Citations

29

References

2001

Year

S. Furue, Katsuya Mikawa, Kahoru Nishina, Makoto Shiga, Masahiko Ueno, Yasuhiko Tomita, Kenji Kuwabara, Isao Teshirogi, Takashi Ono, Yozo Hori,

Critical Care Medicine

Abstract

Our results indicate that therapeutic blockade of sPLA2-IIA ameliorated lung dysfunction via protection of surfactant degradation in an animal model of acute lung injury, and they suggest a new strategy in treating clinical acute lung injury.

References

	Year	Citations

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