Matthew M. Morrissette

The solution phase synthesis of diketopiperazine libraries via the Ugi reaction: Novel application of Armstrong's convertible isonitrile

Christopher Hulme, Matthew M. Morrissette, Francis A. Volz et al. · Tetrahedron Letters · 1998 · 103 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy

Christopher Hulme, Liang Ma, Joseph J. Romano et al. · Tetrahedron Letters · 1999 · 53 citations

Pharmacy, Chemistry, Medicinal Chemistry +5

Dual Inhibition of Phosphodiesterase 4 and Matrix Metalloproteinases by an (Arylsulfonyl)hydroxamic Acid Template

Robert D. Groneberg, Christopher J. Burns, Matthew M. Morrissette et al. · Journal of Medicinal Chemistry · 1999 · 38 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position

Kenneth E. Rittle, James C. Barrow, Kellie J. Cutrona et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 27 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Nanomolar Inhibitors for Two Distinct Biological Target Families from a Single Synthetic Sequence: A Next Step in Combinatorial Library Design?

Christopher J. Burns, Robert D. Groneberg, Joseph M. Salvino et al. · Angewandte Chemie International Edition · 1998 · 22 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17