Joseph J. Romano

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

Steven J. Harper, John A. McCauley, Michael T. Rudd et al. · ACS Medicinal Chemistry Letters · 2012 · 201 citations · Full text

Immunology, Molecular Biology, Pharmacotherapy +19

Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

John A. McCauley, Charles McIntyre, Michael T. Rudd et al. · Journal of Medicinal Chemistry · 2010 · 176 citations

Immunology, Antiviral Drug, Medicinal Chemistry +17

Molecular Modeling Based Approach to Potent P2−P4 Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease

Nigel J. Liverton, M. Katharine Holloway, John A. McCauley et al. · Journal of the American Chemical Society · 2008 · 134 citations

Molecular Docking, Medicinal Chemistry, Initial Compounds +14

Novel applications of carbon dioxide/MeOH for the synthesis of hydantoins and cyclic ureas via the Ugi reaction

Christopher Hulme, Liang Ma, Joseph J. Romano et al. · Tetrahedron Letters · 2000 · 71 citations

Engineering, Biochemistry, Natural Sciences +10