Valeria Chu

In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

Valeria Chu, Heidi J. Einolf, Raymond Evers et al. · Drug Metabolism and Disposition · 2009 · 161 citations

Discovery of an Orally Efficacious Inhibitor of Coagulation Factor Xa Which Incorporates a Neutral P₁Ligand

Yong Mi Choi-Sledeski, Robert E. Kearney, Gregory Poli et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text

Orally Efficacious Inhibitor, Pharmaceutical Science, Pharmacotherapy +18

Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity

Kevin R. Guertin, Charles J. Gardner, Scott I. Klein et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 52 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +10

Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

William R. Ewing, Michael R. Becker, Vincent E. Manetta et al. · Journal of Medicinal Chemistry · 1999 · 42 citations · Full text

Selective Inhibitors, Pharmacotherapy, Chemical Biology +19

Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa

Scott I. Klein, Mark Czekaj, Charles J. Gardner et al. · Journal of Medicinal Chemistry · 1998 · 39 citations · Full text

Vitro Potency, Pharmacotherapy, Initial Structure−activity Relationships +20