Shuichan Xu

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

The PHD Domain of MEKK1 Acts as an E3 Ubiquitin Ligase and Mediates Ubiquitination and Degradation of ERK1/2

Zhimin Lu, Shuichan Xu, Claudio A.P. Joazeiro et al. · Molecular Cell · 2002 · 320 citations · Full text

Protein Function, Signal Transduction, E3 Ubiquitin Ligase +12

Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members

Jeffrey A. Frost, Shuichan Xu, Michele R. Hutchison et al. · Molecular and Cellular Biology · 1996 · 279 citations · Full text

Molecular Regulation, Molecular Biology, Rat Map/erk +17

HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation

Min-Jean Yin, Lori B. Christerson, Yumi Yamamoto et al. · Cell · 1998 · 260 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Derek F. Ceccarelli, Xiaojing Tang, Benoit Pelletier et al. · Cell · 2011 · 230 citations · Full text

Medicine, Allosteric Inhibitor, Drug Development +2