SignalRx Pharmaceuticals (United States)

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

Frank Mercurio, Hengyi Zhu, Brion W. Murray et al. · Science · 1997 · 2K citations

Immunology, Molecular Biology, Inflammation +20

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

Anne‐Claude Gingras, Steven P. Gygi, Brian Raught et al. · Genes & Development · 1999 · 1.3K citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +15

Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2

Anning Lin, Audrey Minden, Horacio Martinetto et al. · Science · 1995 · 773 citations

Immunology, Molecular Biology, Second Protein Kinase +19

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

Joseph A. DiDonato, Frank Mercurio, Caridad Rosette et al. · Molecular and Cellular Biology · 1996 · 709 citations · Full text

Immunology, Molecular Biology, Ikappabalpha Degradation +18

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

Bernd Stein, Maria X. Yang · Molecular and Cellular Biology · 1995 · 693 citations · Full text

Sclerostin, Immunology, Osteoporosis +21