Mark Halliday

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Julie A. Moreno, Helois Radford, Diego Peretti et al. · Nature · 2012 · 596 citations · Full text

Neurodegenerative Diseases, Transcriptional Regulation, Molecular Neuroscience +8

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

Julie A. Moreno, Mark Halliday, Colin Molloy et al. · Science Translational Medicine · 2013 · 566 citations

Creutzfeldt-jakob Disease, Immunology, Cell Death +18

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

Mark Halliday, Helois Radford, Karlijn A. M. Zents et al. · Brain · 2017 · 288 citations · Full text

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

Helois Radford, Julie A. Moreno, Nicholas Verity et al. · Acta Neuropathologica · 2015 · 281 citations · Full text

Neurochemical Biomarkers, Synaptic Signaling, Protein Synthesis +23

Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21

Lisa Michelle Restelli, Björn Oettinghaus, Mark Halliday et al. · Cell Reports · 2018 · 92 citations · Full text