Billy Roberts

Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[<i>d</i>]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Jeff B. Smaill, Brian D. Palmer, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 1999 · 179 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

S. KLUTCHKO, James M. Hamby, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 1998 · 130 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Tyrosine Kinase Inhibitors. 14. Structure−Activity Relationships for Methyl- amino-Substituted Derivatives of 4-[(3-Bromophenyl)amino]-6-(methylamino)- pyrido[3,4-<i>d</i>]pyrimidine (PD 158780), a Potent and Specific Inhibitor of the Tyrosine Kinase Activity of Receptors for the EGF Family of Growth Factors

Gordon W. Rewcastle, Donna K. Murray, William L. Elliott et al. · Journal of Medicinal Chemistry · 1998 · 113 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-<i>d</i>]pyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

S. KLUTCHKO, Hairong Zhou, R. Thomas Winters et al. · Journal of Medicinal Chemistry · 2006 · 79 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Anticancer activity of the structurally novel antibiotic Cl-920 and its analogues.

Wilbur R. Leopold, Joan L. Shillis, Amie E. Mertus et al. · PubMed · 1984 · 78 citations

Medicine, Oncology, Pharmacology +8