Irvin Winkler

Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance 1 1Edited by J. Karn

Y. Hsiou, Kalyan Das, Jianping Ding et al. · Journal of Molecular Biology · 1998 · 123 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication

J P Kleim, R. Bender, U M Billhardt et al. · Antimicrobial Agents and Chemotherapy · 1993 · 115 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants.

J P Kleim, Manfred Rösner, Irvin Winkler et al. · Proceedings of the National Academy of Sciences · 1996 · 83 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Chryseobacterium ureilyticum sp. nov., Chryseobacterium gambrini sp. nov., Chryseobacterium pallidum sp. nov. and Chryseobacterium molle sp. nov., isolated from beer-bottling plants

P Herzog, Irvin Winkler, Dorothee Wolking et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · 2008 · 81 citations

Life Sciences, Biology, Microbiology +17

The antibacterial activity in vitro and β-lactamase stability of the new cephalosporin HR 810 in comparison with five other cephalosporins and two aminoglycosides

Gerhard Seibert, M. Limbert, Irvin Winkler et al. · Infection · 1983 · 52 citations

Life Sciences, Microbiology, Antimicrobial Resistance +10