Wen-Lang Lin

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

Peter E.A. Ash, Kevin F. Bieniek, Tania F. Gendron et al. · Neuron · 2013 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +7

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong‐Jie Zhang, Ya-Fei Xu, Casey Cook et al. · Proceedings of the National Academy of Sciences · 2009 · 616 citations · Full text

Life Sciences, Neurology, Neuroscience +17

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

Radu Stoica, Kurt J. De Vos, Sébastien Paillusson et al. · Nature Communications · 2014 · 597 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice

Ya-Fei Xu, Tania F. Gendron, Yong‐Jie Zhang et al. · Journal of Neuroscience · 2010 · 575 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

Katherine R. Smith, John A. Damiano, Silvana Franceschetti et al. · The American Journal of Human Genetics · 2012 · 492 citations · Full text

Life Sciences, Genetics, Neurology +17