Richard P. Butt

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

Ken McCormack, Sonia Santos, Mark L. Chapman et al. · Proceedings of the National Academy of Sciences · 2013 · 243 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche et al. · Science Translational Medicine · 2016 · 199 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

Aristos J. Alexandrou, Adam R. Brown, Mark L. Chapman et al. · PLoS ONE · 2016 · 194 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy

Aoibhinn McDonnell, Susie M. Collins, Zahid Ali et al. · Pain · 2018 · 175 citations

Medicine, Pharmacology, Pharmacotherapy +17

Mechanical Load Enhances the Stimulatory Effect of Serum Growth Factors on Cardiac Fibroblast Procollagen Synthesis

Richard P. Butt, Jill E. Bishop · Journal of Molecular and Cellular Cardiology · 1997 · 119 citations

Life Sciences, Biochemistry, Physiology +16