BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

Ina Poser, Mihail Sarov, James R. A. Hutchins, +24

Nature Methods

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A Genome-Scale RNAi Screen for Oct4 Modulators Defines a Role of the Paf1 Complex for Embryonic Stem Cell Identity

Li Ding, Maciej Paszkowski‐Rogacz, Anja Nitzsche, +18

Cell stem cell

Developmental BiologyPaf1 ComplexMedicineGeneticsOct4 Modulators +8

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche, +18

Science Translational Medicine

Endothelial S1P ₁ Signaling Counteracts Infarct Expansion in Ischemic Stroke

Anja Nitzsche, Marine Poittevin, Ammar Benarab, +28

Circulation Research

RAD21 Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity

Anja Nitzsche, Maciej Paszkowski‐Rogacz, Filomena Matarese, +9

PLoS ONE

Combined RNAi and localization for functionally dissecting long noncoding RNAs

Debojyoti Chakraborty, Dennis Kappei, Mirko Theis, +9

Nature Methods

Functional GenomicsNatural SciencesRna Structure PredictionRna BiologyMolecular Biology +5

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Eric Engelbrecht, Michel V. Levesque, Liqun He, +13

eLife

Vascular DiseaseImmunologySphingosine 1-Phosphate-regulated TranscriptomesCellular PhysiologyInflammation +25

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons

Nicole Yang, Jörg Isensee, Dylan V. Neel, +27

Nature Neuroscience

Molecular NeuroscienceMolecular PhysiologySignal TransductionMolecular CargoesNeuropathic Pain +8

Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion

Mattias Kalén, Tommi Heikura, Henna Karvinen, +5

PLoS ONE

RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides

K. Matzen, Lina Elzaouk, Alexey A. Matskevich, +3

Nature Biotechnology

Viral ReplicationMolecular BiologyVirologyVirus GeneViral Genetics