Aoibhinn McDonnell

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche et al. · Science Translational Medicine · 2016 · 195 citations

Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy

Aoibhinn McDonnell, Susie M. Collins, Zahid Ali et al. · Pain · 2018 · 158 citations

Pain Therapy, Pain Medicine, Neuropathic Pain +20

Inherited erythromelalgia due to mutations in<i>SCN9A:</i>natural history, clinical phenotype and somatosensory profile

Aoibhinn McDonnell, Betsy R. Schulman, Zahid Ali et al. · Brain · 2016 · 93 citations · Full text

Dimensional phenotypic analysis and functional categorisation of mutations reveal novel genotype–phenotype associations in Rett syndrome

Tony Charman, Tracey C S Neilson, Veronica Mash et al. · European Journal of Human Genetics · 2005 · 57 citations · Full text

Genetic Disorder, Rett Syndrome, Genetics +6

Lack of Detection of the Analgesic Properties of PF‐05089771, a Selective Na_v1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects

Pieter Siebenga, Guido van Amerongen, Justin L. Hay et al. · Clinical and Translational Science · 2019 · 52 citations · Full text