Shen‐Shu Sung

Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor

Liwei Chen, Shen‐Shu Sung, M.L. Richard Yip et al. · Molecular Pharmacology · 2006 · 277 citations

Life Sciences, Molecular Biology, Pharmacology +16

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation

Kenichiro Doi, Rongshi Li, Shen‐Shu Sung et al. · Journal of Biological Chemistry · 2012 · 156 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner

Aslamuzzaman Kazi, Jiazhi Sun, Kenichiro Doi et al. · Journal of Biological Chemistry · 2010 · 121 citations · Full text

Life Sciences, Cancer Biology, Apoptosis +16

A Small-Molecule E2F Inhibitor Blocks Growth in a Melanoma Culture Model

Yihong Ma, Courtney A. Kurtyka, Sandhya Boyapalle et al. · Cancer Research · 2008 · 111 citations · Full text

Medicine, Oncology, Pharmacology +16

Inhibitors of Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds

Harshani R. Lawrence, Roberta Pireddu, Liwei Chen et al. · Journal of Medicinal Chemistry · 2008 · 95 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17