Harshani R. Lawrence

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

Khandaker Siddiquee, Shumin Zhang, Wayne C. Guida et al. · Proceedings of the National Academy of Sciences · 2007 · 738 citations · Full text

Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor

Liwei Chen, Shen‐Shu Sung, M.L. Richard Yip et al. · Molecular Pharmacology · 2006 · 274 citations

A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

Xiaolei Zhang, Ying Sun, Roberta Pireddu et al. · Cancer Research · 2013 · 146 citations · Full text

Novel Inhibitor, Molecular Regulation, Molecular Biology +16

GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors

Aslamuzzaman Kazi, Shengyan Xiang, Hua Yang et al. · Nature Communications · 2018 · 124 citations · Full text

ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer

Kiran Mahajan, Pavani Malla, Harshani R. Lawrence et al. · Cancer Cell · 2017 · 120 citations · Full text

Ar Gene Expression, Chromatin, Systems Biology +9