Harshani R. Lawrence

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

Khandaker Siddiquee, Shumin Zhang, Wayne C. Guida et al. · Proceedings of the National Academy of Sciences · 2007 · 743 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor

Liwei Chen, Shen‐Shu Sung, M.L. Richard Yip et al. · Molecular Pharmacology · 2006 · 277 citations

Life Sciences, Molecular Biology, Pharmacology +16

A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

Xiaolei Zhang, Ying Sun, Roberta Pireddu et al. · Cancer Research · 2013 · 147 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer

Kiran Mahajan, Pavani Malla, Harshani R. Lawrence et al. · Cancer Cell · 2017 · 138 citations · Full text

Medicine, Molecular Biology, Oncology +12

GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors

Aslamuzzaman Kazi, Shengyan Xiang, Hua Yang et al. · Nature Communications · 2018 · 126 citations · Full text

Medicine, Cancer Biology, Oncology +16