Kenichiro Doi

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation

Kenichiro Doi, Rongshi Li, Shen‐Shu Sung et al. · Journal of Biological Chemistry · 2012 · 156 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Rational Design of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors

Avinash Muppidi, Kenichiro Doi, Selvakumar Edwardraja et al. · Journal of the American Chemical Society · 2012 · 149 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner

Aslamuzzaman Kazi, Jiazhi Sun, Kenichiro Doi et al. · Journal of Biological Chemistry · 2010 · 121 citations · Full text

Life Sciences, Cancer Biology, Apoptosis +16

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

Su‐Fern Tan, Xin Liu, Todd E. Fox et al. · Oncotarget · 2016 · 93 citations · Full text

Medicine, Oncology, Pharmacology +13

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

Su‐Fern Tan, Wendy Dunton, Xin Liu et al. · Journal of Lipid Research · 2019 · 50 citations · Full text

Medicine, Oncology, Pharmacology +15