Peter Hodder

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Tsui‐Fen Chou, Steve Brown, Dmitriy Minond et al. · Proceedings of the National Academy of Sciences · 2011 · 323 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

Lars Plate, Christina B. Cooley, John J. Chen et al. · eLife · 2016 · 253 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Small-molecule proteostasis regulators for protein conformational diseases

Barbara Calamini, Maria Catarina Silva, Franck Madoux et al. · Nature Chemical Biology · 2011 · 226 citations

Life Sciences, Biochemistry, Molecular Biology +14

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 208 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Ying Wang, David M. Lonard, Yang Yu et al. · Cancer Research · 2014 · 169 citations

Medicine, Oncology, Pharmacology +17