Prabha N. Ibrahim

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Gideon Bollag, Peter Hirth, James Tsai et al. · Nature · 2010 · 1.8K citations

Medicine, Oncology, Pharmacology +14

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai, John Tayu Lee, Weiru Wang et al. · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +15

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

Elizabeth E. Spangenberg, Paul Severson, Lindsay A. Hohsfield et al. · Nature Communications · 2019 · 998 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

William D. Tap, Zev A. Wainberg, Stephen P. Anthony et al. · New England Journal of Medicine · 2015 · 582 citations

Medicine, Oncology, Pharmacology +15

Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases

G.L. Card, B.P. England, Yoshihisa Suzuki et al. · Structure · 2004 · 431 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14