Paul Severson

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

Elizabeth E. Spangenberg, Paul Severson, Lindsay A. Hohsfield et al. · Nature Communications · 2019 · 894 citations · Full text

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

William D. Tap, Zev A. Wainberg, Stephen P. Anthony et al. · New England Journal of Medicine · 2015 · 571 citations

Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

Robert Wesolowski, Neelesh Sharma, Laura Reebel et al. · Therapeutic Advances in Medical Oncology · 2019 · 161 citations · Full text

BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor

Hatice Gülçin Özer, Dalia El‐Gamal, Ben Powell et al. · Cancer Discovery · 2018 · 135 citations · Full text

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

Sabine U. Vorrink, Paul Severson, Mikhail V. Kulak et al. · Toxicology and Applied Pharmacology · 2013 · 82 citations · Full text

Redox Regulator, Medicine, Liver Physiology +12