Clément Gautier

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.8K citations · Full text

Pink1 Accumulation, Mitophagy, Activate Parkin +18

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

Mitophagy, Cell Death, Molecular Biology +16

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

Clément Gautier, Tohru Kitada, Jie Shen · Proceedings of the National Academy of Sciences · 2008 · 671 citations · Full text

Increased Sensitivity, Mitophagy, Neurodegenerative Diseases +15

Absence of nigral degeneration in aged parkin/DJ‐1/PINK1 triple knockout mice

Tohru Kitada, Youren Tong, Clément Gautier et al. · Journal of Neurochemistry · 2009 · 263 citations · Full text

Aging, Cell Death, Evoked Dopamine Release +16

Federated learning for predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer

Jean Ogier du Terrail, Armand Léopold, Clément Joly et al. · Nature Medicine · 2023 · 173 citations

Breast Oncology, Neoadjuvant Chemotherapy, Medicine +8