Youren Tong

Nigrostriatal Dopaminergic Deficits and Hypokinesia Caused by Inactivation of the Familial Parkinsonism-Linked Gene DJ-1

Matthew S. Goldberg, Antonio Pisani, Marián Haburčák et al. · Neuron · 2005 · 542 citations · Full text

Genetics, Parkinson Disease, Neurology +6

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice

Youren Tong, Hiroo Yamaguchi, Emilie Giaime et al. · Proceedings of the National Academy of Sciences · 2010 · 504 citations · Full text

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

R. Jeremy Nichols, Nicolas Dzamko, Nicholas A. Morrice et al. · Biochemical Journal · 2010 · 397 citations · Full text

Neurodegenerative Diseases, Mitophagy, Signal Transduction +15

LRRK2 regulates synaptic vesicle endocytosis

Narae Shin, Hyerhan Jeong, Jungsun Kwon et al. · Experimental Cell Research · 2008 · 325 citations

Molecular Neuroscience, Signal Transduction, Synaptic Vesicle Endocytosis +7

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice

Youren Tong, Antonio Pisani, Giuseppina Martella et al. · Proceedings of the National Academy of Sciences · 2009 · 308 citations · Full text

Dopaminergic Degeneration, Knockout Mouse, Ki Mice +13