O. Helen Chan

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo et al. · Journal of Medicinal Chemistry · 2000 · 265 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Comparison of Intestinal Permeabilities Determined in Multiple in Vitro and inSitu Models: Relationship to Absorption in Humans

Barbra H. Stewart, O. Helen Chan, Rosalind H. Lu et al. · Pharmaceutical Research · 1995 · 186 citations

Pharmacy, Pharmacokinetics, Physiology +12

Physicochemical and drug-delivery considerations for oral drug bioavailability

O. Helen Chan, Barbra H. Stewart · Drug Discovery Today · 1996 · 146 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Discrimination between drug candidates using models for evaluation of intestinal absorption

Barbra H. Stewart, O. Helen Chan, Nancy Jezyk et al. · Advanced Drug Delivery Reviews · 1997 · 71 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Hydrophobicity of HIV Protease Inhibitors by Immobilized Artificial Membrane Chromatography: Application and Significance to Drug Transport

Barbra H. Stewart, Francis Y. Chung, Bradley D. Tait et al. · Pharmaceutical Research · 1998 · 36 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +16