A rapid screening test to determine the antioxidant potencies of natural and synthetic antioxidants

William A. Pryor, Joseph A. Cornicelli, Larry J. Devall, +4

The Journal of Organic Chemistry

Antioxidant PotenciesBiochemistryMedicineLipid PeroxidationAltmetric Attention Score +8

Reversal of .pi.-facial diastereoselection upon electronegative substitution of the substrate and the reagent

Andrzej Stanisław Cieplak, Bradley D. Tait, Carl R. Johnson

Journal of the American Chemical Society

Molecular SciencesEngineeringChemical MeasurementOphthalmologyBiochemistry +11

Small-molecule proteostasis regulators for protein conformational diseases

Barbara Calamini, Maria Catarina Silva, Franck Madoux, +9

Nature Chemical Biology

Protein FunctionProtein FoldingNatural SciencesMedicineSmall-molecule Proteostasis Regulators +5

Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties

Sandra M. Sendobry, Joseph A. Cornicelli, Kathryn Welch, +7

British Journal of Pharmacology

Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

J. V. N. Vara Prasad, Kimberly S. Para, Elizabeth A. Lunney, +6

Journal of the American Chemical Society

Molecular PharmacologyMedicinal ChemistryNovel SeriesLow Molecular WeightMedicine +13

A cerium(III) modification of the Peterson reaction: methylenation of readily enolizable carbonyl compounds

Carl R. Johnson, Bradley D. Tait

The Journal of Organic Chemistry

Chemical EngineeringChemical MeasurementEngineeringDerivative (Chemistry)Chemical Analysis +12

A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Elizabeth A. Lunney, Susan E. Hagen, John M. Domagala, +6

Journal of Medicinal Chemistry

Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators and Correctors

Kenneth A. Giuliano, Shinichiro Wachi, Lawrence Drew, +9

SLAS DISCOVERY

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors:  The Profound Effect of Polarity on Antiviral Activity

Susan E. Hagen, J. V. N. Vara Prasad, F Boyer, +15

Journal of Medicinal Chemistry

Altmetric Attention ScoreWarner LambertAntiviral DrugChemical BiologyPharmaceutical Chemistry +16

4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease:  The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters

Susan E. Hagen, John M. Domagala, Christopher Gajda, +15

Journal of Medicinal Chemistry

Heterocyclic SubstituentsAntiviral DrugPharmaceutical ChemistryMedicinal ChemistryMutant Hiv Protease +15