Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

J. V. N. Vara Prasad, Kimberly S. Para, Elizabeth A. Lunney, +6

Journal of the American Chemical Society

Molecular PharmacologyMedicinal ChemistryNovel SeriesLow Molecular WeightMedicine +13

Discovery of a Highly Selective Glycogen Synthase Kinase‐3 Inhibitor (PF‐04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging

Steven H. Liang, Jinshan Michael Chen, Marc D. Normandin, +29

Angewandte Chemie International Edition

Structure-Based Design of a Novel Series of Nonpeptide Ligands That Bind to the pp60^src SH2 Domain

Elizabeth A. Lunney, Kimberly S. Para, John R. Rubin, +4

Journal of the American Chemical Society

EngineeringNonpeptide LigandsMolecular BiologyChemistrySh2 Domain +14

The Role of 4-phosphonodifluoromethyl- and 4-phosphono-phenylalanine in the selectivity and cellular uptake of SH2 domain ligands

Charles J. Stankovic, Narayanan Surendran, Elizabeth A. Lunney, +11

Bioorganic & Medicinal Chemistry Letters

Proteinlipid InteractionBiochemistryNatural SciencesCellular UptakeMedicine +8

Design and synthesis of phenethyl benzo[1,4]oxazine-3-ones as potent inhibitors of PI3Kinaseγ

Thomas Lanni, Keri L. Greene, Christine N. Kolz, +6

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryNatural SciencesMedicinePhenethyl Benzo +6

Nonpeptidic Potent HIV-1 Protease Inhibitors: (4-Hydroxy-6-phenyl-2-oxo-2H-pyran-3-yl)thiomethanes That Span P1-P2' Subsites in a Unique Mode of Binding

J. V. N. Vara Prasad, Kimberly S. Para, Peter J. Tummino, +6

Journal of Medicinal Chemistry

Design of peptidomimetic ligands for the pp60src SH2 domain

Mark S. Plummer, Elizabeth A. Lunney, Kimberly S. Para, +9

Bioorganic & Medicinal Chemistry

Molecular ComplexPeptoidPp60src Sh2 DomainBiomolecular Engineering

Novel phosphotyrosine mimetics in the design of peptide ligands for pp60src SH2 domain

Aurash Shahripour, Mark S. Plummer, Elizabeth A. Lunney, +10

Bioorganic & Medicinal Chemistry Letters

BiochemistryPeptide EngineeringPeptide LibraryPp60src Sh2 DomainPeptide Synthesis +4

Discovery and optimization of nonpeptide HIV-1 protease inhibitors

Peter J. Tummino, J. V. N. Vara Prasad, Donna Ferguson, +14

Bioorganic & Medicinal Chemistry

BiochemistryAntiviral Drug DevelopmentRational Drug DesignHivMedicine +2

Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition

Paul V. Fish, Christopher Deur, Xinmin Gan, +10

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryDual SerotoninDerivative (Chemistry) +13