Discrimination between drug candidates using models for evaluation of intestinal absorption

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

Medicine, Gastroenterology, Pathology +10

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.8K citations

Health Sciences, Medicine, Physiology +9

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

M. Pinto · SPIRE - Sciences Po Institutional REpository · 1983 · 1.8K citations · Full text

A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of d-glucose and choline transport systems

Markus Kessler, Oreste Acuto, Carlo Storelli et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1978 · 1.1K citations

Membrane Formation, Engineering, Choline Transport Systems +10

Intestinal Epithelial Cell Surface Membrane Glycoprotein Synthesis

Milton M. Weiser · Journal of Biological Chemistry · 1973 · 1.1K citations · Full text

Glycobiology, Pathology, Cell Culture +16