Concepedia

Multi-compartment Absorption Models

Multi-Compartment Absorption Models is a pharmacokinetic modeling framework that partitions the absorption process into multiple sequential or parallel physiological compartments to account for regional differences in drug transit, dissolution, and permeability along the gastrointestinal tract.

45

Publications

3.3K

Citations

158

Authors

65

Institutions

Publications per year

2017–2026

3

Variants

Multi-compartment Absorption Model

Parents

Publications

45

A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine

Mans Minekus, Phillipe Marteau, R. Havenaar et al. · Alternatives to Laboratory Animals · 1995 · 667 citations

, , +17

A compartmental absorption and transit model for estimating oral drug absorption

Lawrence X. Yu, Gordon L. Amidon · International Journal of Pharmaceutics · 1999 · 450 citations

, , +16

Compartmental transit and dispersion model analysis of small intestinal transit flow in humans

Lawrence X. Yu, John R. Crison, Gordon L. Amidon · International Journal of Pharmaceutics · 1996 · 232 citations

, , +16

Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes

Ichiro Komiya, J.Y. Park, A. Kamani et al. · International Journal of Pharmaceutics · 1980 · 228 citations · Full text

, , +17

Localization of Human Thyroxine Absorption

Marguerite T. Hays · Thyroid · 1991 · 139 citations

, , +17

1–5 of 45

Authors

158

  1. WI
    William I. Higuchi

    University of Utah, United States

    4 publications · 459 citations

    4

    h-index

  2. NF
    Norman F.H. Ho

    University of Michigan, United States

    4 publications · 459 citations

    4

    h-index

  3. GL
    Gordon L. Amidon

    University of Michigan, United States

    4 publications · 740 citations

    3

    h-index

  4. KS
    K. Sandy Pang

    University of Toronto, Canada

    3 publications · 140 citations

    3

    h-index

  5. EC
    Edwin C.Y. Chow

    University of Toronto, Canada

    2 publications · 70 citations

    2

    h-index

1–5 of 158

Institutions

65

  1. University of Michigan

    Ann Arbor, United States

    9 h-index

    37 publications

    3.4K citations

  2. United States Food and Drug Administration

    Silver Spring, United States

    2 h-index

    3 publications

    103 citations

  3. University of Toronto

    Toronto, Canada

    2 h-index

    2 publications

    105 citations

  4. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    2 h-index

    12 publications

    964 citations

  5. University College London

    London, United Kingdom

    2 h-index

    4 publications

    196 citations

  6. Universitat de València

    Valencia, Spain

    1 h-index

    6 publications

    84 citations

  7. Queen Charlotte's and Chelsea Hospital

    London, United Kingdom

    1 h-index

    2 publications

    44 citations

  8. Imaging Technology Consulting (United States)

    Knoxville, United States

    1 h-index

    3 publications

    111 citations

1–8 of 65

Venues

  1. Journal of Pharmaceutical Sciences

    7 publications · 347 citations

    7

    h-index

  2. International Journal of Pharmaceutics

    5 publications · 951 citations

    5

    h-index

  3. Drug Metabolism and Disposition

    4 publications · 172 citations

    4

    h-index

  4. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 2 publications · 43 citations

    2

    h-index

  5. 2

    h-index

1–5