Stephen Schmidt

Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

Mala V. Rao, Panaiyur S. Mohan, Corrinne M. Peterhoff et al. · Journal of Neuroscience · 2008 · 106 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis

Chudi Ndubaku, Terry D. Crawford, Huifen Chen et al. · ACS Medicinal Chemistry Letters · 2015 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Combination Drug Scheduling Defines a “Window of Opportunity” for Chemopotentiation of Gemcitabine by an Orally Bioavailable, Selective ChK1 Inhibitor, GNE-900

Elizabeth Blackwood, Jennifer Epler, Ivana Yen et al. · Molecular Cancer Therapeutics · 2013 · 37 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1

Lewis Gazzard, B.A. Appleton, Kerry L. Chapman et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1

Lewis Gazzard, Karen Williams, Huifen Chen et al. · Journal of Medicinal Chemistry · 2015 · 18 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17