Elizabeth Blackwood

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 346 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function

Elaine E. Storm, Steffen Durinck, Felipe de Sousa e Melo et al. · Nature · 2015 · 252 citations

Medicine, Cancer Biology, Oncology +14

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-p <i>K</i> _a Polar Moiety

Chudi Ndubaku, James J. Crawford, Joy Drobnick et al. · ACS Medicinal Chemistry Letters · 2015 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Phosphoproteomic Analysis Implicates the mTORC2-FoxO1 Axis in VEGF Signaling and Feedback Activation of Receptor Tyrosine Kinases

Guanglei Zhuang, Kebing Yu, Zhaoshi Jiang et al. · Science Signaling · 2013 · 82 citations

Life Sciences, Biochemistry, Molecular Biology +17

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Joachim Rudolph, Lesley Murray, Chudi Ndubaku et al. · Journal of Medicinal Chemistry · 2016 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13