USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé, +41

Nature

Molecular DockingUbiquitin BindingDrug TargetMedicineNatural Sciences +5

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Ingrid E. Wertz, Kim Newton, Dhaya Seshasayee, +31

Nature

InflammationAnti-inflammatoryAutoimmune DiseaseMedicineImmunology +5

Selective activation of PFKL suppresses the phagocytic oxidative burst

Neri Amara, Madison P. Cooper, Maria A. Voronkova, +12

Cell

Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death

M. Cristina de Almagro, Tatiana Goncharov, Anita Izrael-Tomasevic, +11

Cell Death and Differentiation

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling

Tatiana Goncharov, Stefanie Hedayati, Melinda M. Mulvihill, +12

Molecular Cell

InflammationCytokineAutoimmune DiseaseImmunologyChronic Inflammation +5

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

Steffan Vartanian, P. Taylur, James Lee, +4

Molecular & Cellular Proteomics

Mammalian liver cytochrome c is tyrosine-48 phosphorylated in vivo, inhibiting mitochondrial respiration

Hong Yu, Icksoo Lee, Arthur R. Salomon, +2

Biochimica et Biophysica Acta (BBA) - Bioenergetics

New Prospects for an Old Enzyme:  Mammalian Cytochrome<i> c</i> Is Tyrosine-Phosphorylated in Vivo

Icksoo Lee, Arthur R. Salomon, Kebing Yu, +3

Biochemistry

The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function

Nina Oberbeck, Victoria C. Pham, Joshua D. Webster, +15

Nature

Transcriptional RegulationSignal TransductionDevelopmental BiologySignaling PathwayCell Regulation +6

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

David S. Hewings, Johanna Heideker, P. Taylur, +15

Nature Communications