Florian Schmidt

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Ryan D. Chow, Christopher D. Guzman, Guangchuan Wang et al. · Nature Neuroscience · 2017 · 243 citations · Full text

Off-target Effect, Glioma, Genome Engineering +8

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy

Leonela Amoasii, Chengzu Long, Hui Li et al. · Science Translational Medicine · 2017 · 243 citations · Full text

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

Chady H. Hakim, Sandeep Kumar, Dennis O. Pérez‐López et al. · Nature Communications · 2021 · 161 citations · Full text

Transcriptional recording by CRISPR spacer acquisition from RNA

Florian Schmidt, Mariia Y. Cherepkova, Randall J. Platt · Nature · 2018 · 151 citations · Full text

Transcriptional Regulation, Crispr Spacer Acquisition, Genetics +6

Noninvasive assessment of gut function using transcriptional recording sentinel cells

Florian Schmidt, Jakob Zimmermann, Tanmay Tanna et al. · Science · 2022 · 87 citations · Full text