Concepedia
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Publications
8
Citations
815
H-Index
Active since
1998
Affiliations
Cytokinetics (United States)(Current)
Menlo School
Donghong Xu is an author at Cytokinetics (United States) specializing in drug discovery, medicinal chemistry, and pharmacy.
Publications per year
1998–2024
The Presenilin 1 Protein Is a Component of a High Molecular Weight Intracellular Complex That Contains β-Catenin
Gang Yu, Fusheng Chen, Georges Lévesque et al. · Journal of Biological Chemistry · 1998 · 369 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +12
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 190 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +17
Discovery of<i>Omecamtiv Mecarbil</i>the First, Selective, Small Molecule Activator of Cardiac Myosin
B. Paul Morgan, Alexander R. Muci, Pu‐Ping Lu et al. · ACS Medicinal Chemistry Letters · 2010 · 112 citations · Full text
A Phase 1 Dose-Escalation Study of the Cardiac Myosin Inhibitor Aficamten in Healthy Participants
Fady I. Malik, Laura Robertson, Danielle Armas et al. · JACC Basic to Translational Science · 2022 · 64 citations · Full text
Medicine, Pharmacokinetics, Pharmacology +15
Discovery of<i>Tirasemtiv</i>, the First Direct Fast Skeletal Muscle Troponin Activator
Scott E. Collibee, Gustave Bergnes, Alexander R. Muci et al. · ACS Medicinal Chemistry Letters · 2018 · 30 citations · Full text
Pharmacy, Biochemistry, Medicinal Chemistry +8
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