Hongying Yang

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Diabetes Management, Medicine, Diabetes +9

Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

Hongying Yang, Tianle Yang, Joseph A. Baur et al. · Cell · 2007 · 928 citations · Full text

Mitochondrial Function, Biochemistry, Physiology +4

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

Hongying Yang, Wei Zhang, Heng Pan et al. · PLoS ONE · 2012 · 358 citations · Full text

Immunology, Immune Regulation, Innate Immunity +16

Design and synthesis of compounds that extend yeast replicative lifespan

Hongying Yang, Joseph A. Baur, Allen Chen et al. · Aging Cell · 2006 · 105 citations · Full text

MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase.

Boguslaw Stec, Mary F. Roberts, Hongying Yang et al. · Nature Structural Biology · 2000 · 89 citations

Biosynthesis, Biochemistry, Natural Sciences +6