Zhenhua Chen

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li et al. · Cancer Cell · 2020 · 742 citations · Full text

Immune Evasion, Medicine, Stem Cell Mobilization +8

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huilin Huang, Hengyou Weng, Keren Zhou et al. · Nature · 2019 · 681 citations

Histone Modifications, Chromatin, Transcriptional Regulation +14

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

Ying Qing, Lei Dong, Lei Gao et al. · Molecular Cell · 2021 · 332 citations · Full text

Biochemistry, Medicine, Catabolism +8

METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis

Rui Su, Lei Dong, Yangchan Li et al. · Nature Cell Biology · 2022 · 331 citations · Full text

Signaling Pathway, Translational Biology, Cell Regulation +10

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Hengyou Weng, Feng Huang, Zhaojin Yu et al. · Cancer Cell · 2022 · 281 citations · Full text

Hematological Malignancy, Glutamine Metabolism, Medicine +8