Lei Gao

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li et al. · Cancer Cell · 2020 · 742 citations · Full text

Immune Evasion, Medicine, Stem Cell Mobilization +8

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

Ying Qing, Lei Dong, Lei Gao et al. · Molecular Cell · 2021 · 332 citations · Full text

Biochemistry, Medicine, Catabolism +8

METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis

Rui Su, Lei Dong, Yangchan Li et al. · Nature Cell Biology · 2022 · 331 citations · Full text

Signaling Pathway, Translational Biology, Cell Regulation +10

QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

Zhicong Zhao, Ying Qing, Lei Dong et al. · Cell · 2023 · 162 citations · Full text

Internal M7g-modified Transcripts, Signal Transduction, Protein Expression +9

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

Li Han, Lei Dong, Keith Leung et al. · Cell stem cell · 2023 · 142 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +8