Junyan Wang

Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

Junyan Wang, Bo Deng, Qing Liu et al. · Cell Death and Disease · 2020 · 226 citations · Full text

Life Sciences, Cardiology, Cell Biology +14

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

Shaoyong Lu, Xinheng He, Zhao Yang et al. · Nature Communications · 2021 · 222 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis

Ruijia Wen, Xin Dong, Haowen Zhuang et al. · Phytomedicine · 2023 · 193 citations

Medicine, Cancer Biology, Oncology +6

Nuclear receptor subfamily 4 group A member 1 promotes myocardial ischemia/reperfusion injury through inducing mitochondrial fission factor-mediated mitochondrial fragmentation and inhibiting FUN14 domain containing 1-depedent mitophagy

Junyan Wang, Haowen Zhuang, Lianqun Jia et al. · International Journal of Biological Sciences · 2024 · 168 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

SIRT5‐Related Desuccinylation Modification Contributes to Quercetin‐Induced Protection against Heart Failure and High‐Glucose‐Prompted Cardiomyocytes Injured through Regulation of Mitochondrial Quality Surveillance

Xing Chang, Tian Zhang, Junyan Wang et al. · Oxidative Medicine and Cellular Longevity · 2021 · 104 citations · Full text

Medicine, Cardiology, Pharmacology +17