NAD+ metabolism governs the proinflammatory senescence-associated secretome

Timothy Nacarelli, Lena Lau, Takeshi Fukumoto, +14

Nature Cell Biology

Cellular SenescenceNad+ MetabolismMedicineCell BiologyOxidative Stress

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Benjamin G. Bitler, Shuai Wu, Pyoung Hwa Park, +14

Nature Cell Biology

Hdac6 ActivityCancer GeneticsMedicineRadiation OncologyTumor Biology +1

N6-Methylation of Adenosine of <i>FZD10</i> mRNA Contributes to PARP Inhibitor Resistance

Takeshi Fukumoto, Hengrui Zhu, Timothy Nacarelli, +9

Cancer Research

Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma

Shuai Wu, Takeshi Fukumoto, Jianhuang Lin, +18

Nature Cancer

Oncogenic AgentMedicineGls1 InhibitionTumor SuppressorGlutamine Dependence +5

The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II

Marco Trizzino, Elisa Barbieri, Ana Petracovici, +6

Cell Reports

Rna Polymerase IiGeneticsExclusive SubunitsEstrogen ReceptorTumor Biology +17

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer

Takeshi Fukumoto, Pyoung Hwa Park, Shuai Wu, +12

Cell Reports

CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity

Sergey Karakashev, Hengrui Zhu, Shuai Wu, +12

Nature Communications

Epigenetic ChangeGynecologyCancer BiologyEpigeneticsTumor Biology +15

SNORD126 promotes HCC and CRC cell growth by activating the PI3K–AKT pathway through FGFR2

Xian-Long Fang, Dongmei Yang, Hongping Luo, +8

Journal of Molecular Cell Biology

PathologyCell ProliferationCancer BiologyTumor BiologySignaling Pathway +16

Deep shale gas exploration and development in the southern Sichuan Basin: New progress and challenges

Xiao He, Gengsheng Chen, Jianfa Wu, +4

Natural Gas Industry B

Evolution and heterogeneity of non-hereditary colorectal cancer revealed by single-cell exome sequencing

Hongjin Wu, XY Zhang, Zhaoyang Hu, +10

Oncogene

OncologyTumor HeterogeneityMedicineSingle Cell SequencingNon-hereditary Colorectal Cancer +10