Benjamin G. Bitler

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

Benjamin G. Bitler, Katherine M. Aird, Azat Garipov et al. · Nature Medicine · 2015 · 660 citations · Full text

Tumor Biology, Radiation Oncology, Oncogenic Agent +10

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

Hengrui Zhu, Fee Bengsch, Nikolaos Svoronos et al. · Cell Reports · 2016 · 417 citations · Full text

Cancer Immunosurveillance, Pd-l1 Expression, Pd-l1 Signaling +10

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

Katherine M. Aird, Gao Zhang, Hua Li et al. · Cell Reports · 2013 · 290 citations · Full text

Oncogene-induced Senescence, Reductive Stress, Genome Instability +15

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Benjamin G. Bitler, Shuai Wu, Pyoung Hwa Park et al. · Nature Cell Biology · 2017 · 223 citations

Hdac6 Activity, Cancer Genetics, Medicine +3

Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy

Jing Li, Weichao Wang, Yajia Zhang et al. · Journal of Clinical Investigation · 2020 · 193 citations · Full text

Genetics, Immunology, Immunotherapy +18