Liying Zhang

QSAR Modeling of the Blood–Brain Barrier Permeability for Diverse Organic Compounds

Liying Zhang, Hao Zhu, Tudor I. Oprea et al. · Pharmaceutical Research · 2008 · 199 citations

Pharmaceutical Science, Qsar Modeling, Blood–brain Barrier Permeability +7

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Discovery of Novel Antimalarial Compounds Enabled by QSAR-Based Virtual Screening

Liying Zhang, Denis Fourches, Alexander Sedykh et al. · Journal of Chemical Information and Modeling · 2012 · 96 citations · Full text

Antiparasitic Agent, Malaria, Pharmaceutical Chemistry +18

Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches

Liying Zhang, Alexander Sedykh, Ashutosh Tripathi et al. · Toxicology and Applied Pharmacology · 2013 · 81 citations · Full text

Endocrine Disruptors, Virtual Screening, Hit Identification +9

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

Jonathan L. Chen, Peiyuan Zhang, Masahito Abe et al. · Journal of the American Chemical Society · 2020 · 78 citations · Full text

Analogue Synthesis, Molecular Biology, Lead Identification +19