Carlo Federico Perno

1,2,3-Triazole-[2,5-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) (TSAO) Analogs: Synthesis and Anti-HIV-1 Activity

Rosa Álvarez, Sonsoles Velázquez, Ana San‐Félix et al. · Journal of Medicinal Chemistry · 1994 · 750 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

Robert Yarchoan, Hiroaki Mitsuya, Rose V. Thomas et al. · Science · 1989 · 425 citations

Medicine, Infectious Diseases, Pharmacology +17

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

Carlo Federico Perno, Robert Yarchoan, David A. Cooney et al. · The Journal of Experimental Medicine · 1989 · 290 citations · Full text

Life Sciences, Immunology, Microbiology +14

Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative

Masanori Baba, H. TANAKA, Erik De Clercq et al. · Biochemical and Biophysical Research Communications · 1989 · 288 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

John Gregson, Michele W. Tang, Nicaise Ndembi et al. · The Lancet Infectious Diseases · 2016 · 275 citations · Full text

Public Health, Pharmacology, Pharmacotherapy +17