Takahito Hara

Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome.

Takahito Hara, Jun‐ichi Miyazaki, Hideo Araki et al. · PubMed · 2003 · 427 citations

Molecular Pharmacology, Androgen Receptor, Urology +12

Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response

Akito Nakamura, Tadahiro Nambu, Shunsuke Ebara et al. · Proceedings of the National Academy of Sciences · 2018 · 160 citations · Full text

Tumor Biology, Oncology, Amino Acid Response +14

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

Tomohiro Kaku, Takenori Hitaka, Akio Ojida et al. · Bioorganic & Medicinal Chemistry · 2011 · 126 citations · Full text

Medicinal Chemistry, Selective 17,20-Lyase Inhibitor, Potential Utility +9

Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys

Masuo Yamaoka, Takahito Hara, Takenori Hitaka et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 116 citations

Steroid Synthesis, Medicinal Chemistry, Adrenal Gland +10

Androgen Receptor and Invasion in Prostate Cancer

Takahito Hara, Hideyo Miyazaki, Aram Lee et al. · Cancer Research · 2008 · 114 citations · Full text