Takahito Hara

Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome.

Takahito Hara, Jun‐ichi Miyazaki, Hideo Araki et al. · PubMed · 2003 · 427 citations

Medicine, Endocrinology, Pharmacology +17

Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response

Akito Nakamura, Tadahiro Nambu, Shunsuke Ebara et al. · Proceedings of the National Academy of Sciences · 2018 · 170 citations · Full text

Medicine, Oncology, Pharmacology +16

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

Tomohiro Kaku, Takenori Hitaka, Akio Ojida et al. · Bioorganic & Medicinal Chemistry · 2011 · 126 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys

Masuo Yamaoka, Takahito Hara, Takenori Hitaka et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 116 citations

Life Sciences, Endocrinology, Pharmacology +17

Androgen Receptor and Invasion in Prostate Cancer

Takahito Hara, Hideyo Miyazaki, Aram Lee et al. · Cancer Research · 2008 · 114 citations · Full text

Medicine, Cancer Biology, Oncology +16