The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki, +22

Nature Medicine

Insulin ResistanceMetabolic SyndromeObesityMetabolic DisorderBiochemistry +9

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, +23

Nature

ObesityMetabolic SyndromeBiochemistryMedicineInsulin Management +5

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

Jeffrey D. Rothstein, Margaret Dykes‐Hoberg, Carlos A. Pardo, +7

Neuron

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst, +7

New England Journal of Medicine

Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

Atsushi Enomoto, Hiroaki Kimura, Arthit Chairoungdua, +15

Nature

UrologyMolecular PhysiologyRenal FunctionRenal Urate–anion ExchangerMedicine +8

HRS Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis

David H. Birnie, William H. Sauer, Frank Bogun, +11

Heart Rhythm

Cardiac SarcoidosisArrhythmias AssociatedCardiomyopathyCardiovascular DiseaseMyocardial Infarction +7

Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study

Masaaki Yamamoto, Toru Serizawa, Takashi Shuto, +30

The Lancet Oncology

Neuro-oncologyMultiple Brain MetastasesRadiation TherapyMedicineSurgery +6

Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma

Ghassan K. Abou‐Alfa, George Lau, Masatoshi Kudo, +27

NEJM Evidence

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis

Bruce E. Sands, William J. Sandborn, Remo Panaccione, +13

New England Journal of Medicine

Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

Yoshikatsu Kanai, Hiroko Segawa, Ken‐ichi Miyamoto, +3

Journal of Biological Chemistry

Functional PropertiesImmunologyExpression CloningAntigen ProcessingGlioma +18