Tomoya Muto

Concurrent loss of <i>Ezh2</i> and <i>Tet2</i> cooperates in the pathogenesis of myelodysplastic disorders

Tomoya Muto, Goro Sashida, Motohiko Oshima et al. · The Journal of Experimental Medicine · 2013 · 174 citations · Full text

Medicine, Genetics, Hematology +17

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

Goro Sashida, Hironori Harada, Hirotaka Matsui et al. · Nature Communications · 2014 · 169 citations · Full text

Medicine, Genetics, Molecular Genetics +12

Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

Tomoya Muto, Callum S. Walker, Kwangmin Choi et al. · Nature Immunology · 2020 · 153 citations · Full text

Life Sciences, Cell Biology, Hematology +16

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner

Makiko Mochizuki‐Kashio, Kazumasa Aoyama, Goro Sashida et al. · Blood · 2015 · 135 citations · Full text

Life Sciences, Genetics, Hematology +16

TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis

Jing Fang, Tomoya Muto, Maria Kleppe et al. · Cell Reports · 2018 · 78 citations · Full text

Life Sciences, Cell Biology, Immunology +16