Motohiko Oshima

Concurrent loss of <i>Ezh2</i> and <i>Tet2</i> cooperates in the pathogenesis of myelodysplastic disorders

Tomoya Muto, Goro Sashida, Motohiko Oshima et al. · The Journal of Experimental Medicine · 2013 · 174 citations · Full text

Epigenetic Change, Genetics, Pathology +20

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

Goro Sashida, Hironori Harada, Hirotaka Matsui et al. · Nature Communications · 2014 · 164 citations · Full text

Hematological Malignancy, Chromatin, Developmental Biology +9

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner

Makiko Mochizuki‐Kashio, Kazumasa Aoyama, Goro Sashida et al. · Blood · 2015 · 134 citations · Full text

Role of SOX17 in hematopoietic development from human embryonic stem cells

Yaeko Nakajima‐Takagi, Mitsujiro Osawa, Motohiko Oshima et al. · Blood · 2012 · 103 citations

The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition

Goro Sashida, Changshan Wang, T. Tomioka et al. · The Journal of Experimental Medicine · 2016 · 95 citations · Full text

Immunology, Pathology, Cancer Biology +16