Andrew C. Flick

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Rhodium(II)-Catalyzed Aziridination of Allyl-Substituted Sulfonamides and Carbamates

Albert Padwa, Andrew C. Flick, Carolyn A. Leverett et al. · The Journal of Organic Chemistry · 2004 · 144 citations

Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis

Daniel C. Schmitt, Alexandria P. Taylor, Andrew C. Flick et al. · Organic Letters · 2015 · 62 citations

1,3-Diols Engage, Engineering, 1,4-Disubstituted Pyrazoles +8

Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities

Eugene L. Piatnitski Chekler, Jessica Pellegrino, Thomas A. Lanz et al. · Chemistry & Biology · 2015 · 60 citations · Full text

Transcriptional Regulation, Transcriptional Profiling, Signaling Pathway +10

Synthetic Approaches to New Drugs Approved during 2018

Andrew C. Flick, Hong X. Ding, Emma L. McInturff et al. · Journal of Medicinal Chemistry · 2020 · 50 citations

Drug Target, Chemical Biology, Molecular Pharmacology +21