Renate Schnitzer

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

William Farnaby, Manfred Koegl, Michael J. Roy et al. · Nature Chemical Biology · 2019 · 576 citations · Full text

Life Sciences, Bioinformatics, Oncology +9

Drugging an undruggable pocket on KRAS

Dirk Kessler, Michael Gmachl, Andreas Mantoulidis et al. · Proceedings of the National Academy of Sciences · 2019 · 434 citations · Full text

Medicine, Molecular Biology, Oncology +15

Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6

Nina Kerres, Steffen Steurer, Stefanie Schlager et al. · Cell Reports · 2017 · 206 citations · Full text

Medicine, Cancer Biology, Molecular Biology +11

Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors

Harald Engelhardt, Dietrich Böse, Mark Petronczki et al. · Journal of Medicinal Chemistry · 2019 · 145 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of Novel Spiro[3<i>H</i>-indole-3,2′-pyrrolidin]-2(1<i>H</i>)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2–p53 Interaction

Andreas Gollner, Dorothea Rudolph, Heribert Arnhof et al. · Journal of Medicinal Chemistry · 2016 · 121 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16