Mustapha Haddach - Concepedia

Author

Mustapha Haddach

Neurocrine Biosciences (United States)

Also Known As

Haddach, Mustapha, M. HADDACH, M. Haddach, Mustapha Haddach

Publications

2.7K

Citations

H-Index

Concepts

All Affiliations

Neurocrine Biosciences (United States)The University of Melbourne Peter MacCallum Cancer Centre Monash University Cytel (United States)

About

Mustapha Haddach is an author at Neurocrine Biosciences (United States) specializing in drug discovery, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	900
2	Biochemistry	7	7	404
3	Natural Sciences	6	6	339
4	Engineering	2	2	329
5	Biomolecular Engineering	2	2	329

Mustapha Haddach

Publications

2.6K

Citations

H-Index

Page 1

	Year	Citations
Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth Denis Drygin, Amy Lin, Josh Bliesath, Cancer Research	2010	610
Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 Megan J. Bywater, Gretchen Poortinga, Elaine Sanij, Cancer Cell	2012	552
Discovery and SAR of 5-(3-Chlorophenylamino)benzo[<i>c</i>][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer Fabrice Pierre, Peter Chua, Sean O’Brien, Journal of Medicinal Chemistry	2010	295
A new method for the synthesis of ketones: The palladium-catalyzed cross-coupling of acid chlorides with arylboronic acids Mustapha Haddach, James R. McCarthy Tetrahedron Letters Arylboronic AcidsCross-coupling ReactionEnantioselective SynthesisEngineeringPalladium-catalyzed Cross-coupling	1999	173
Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer Roberto Battistutta, Giorgio Cozza, Fabrice Pierre, Biochemistry Crystal StructureMolecular BiologyChemical BiologyTumor BiologyMedicinal Chemistry	2011	170
Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics Mustapha Haddach, Michael K. Schwaebe, Jerome Michaux, ACS Medicinal Chemistry Letters EngineeringRna PolMolecular BiologyPharmaceutical ChemistryNucleic Acid Biomarkers	2012	156
Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer Fabrice Pierre, Peter Chua, Sean O’Brien, Molecular and Cellular Biochemistry MedicineCancer GrowthImmune Checkpoint InhibitorAnti-cancer AgentPre-clinical Characterization	2011	151
Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor Mustapha Haddach, Jerome Michaux, Michael K. Schwaebe, ACS Medicinal Chemistry Letters Pim KinasesPharmacotherapyA PotentCompound 13Tumor Biology	2011	84
Potential Use of Selective and Nonselective Pim Kinase Inhibitors for Cancer Therapy Denis Drygin, Mustapha Haddach, Fabrice Pierre, Journal of Medicinal Chemistry Cancer TherapyMolecular PharmacologyMedicineApt 40Pharmacology	2012	70
Potent imidazole and triazole CB 1 receptor antagonists related to SR141716 Brian Dyck, Val S. Goodfellow, Teresa A. Phillips, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyBiochemistryFunctional SelectivityMedicineReceptor Antagonists	2004	65

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